Bean's film roles include Patriot Games (1992), GoldenEye (1995), Ronin (1998), Don't Say a Word (2001), The Lord of the Rings trilogy (2001–2003), Equilibrium (2002), National Treasure (2004), Troy (2004), Flightplan (2005), North Country (2005), The Island (2005), Silent Hill (2006), Percy Jackson & the Olympians: The Lightning Thief (2010), Black Death (2010), Jupiter Ascending (2015), and The Martian (2015).
His television roles include the BBC anthology series Accused, Broken, Game of Thrones, and the ITV historical drama series Henry VIII and Legends. As a voice actor, Bean has been featured in the video games The Elder Scrolls IV: Oblivion, Sid Meier's Civilization VI, and the feature films Wolfwalkers and Mummies among others. Bean has also been the main voice over for O2 and their adverts for over 20 years having originally taken the job in 2002.
In 2022, Bean won the British Academy Television Award as Leading Actor in Time, a BBC One drama.