Kravitz earned acclaim for her lead roles in the HBO drama series Big Little Lies (2017–2019), which earned her a Screen Actors Guild Award nomination, and the Hulu romantic comedy series High Fidelity (2020), for which she won a Black Reel Award and received a nomination for a Satellite Award. She voiced Catwoman in The Lego Batman Movie (2017), and will reprise the role in Matt Reeves' DC film The Batman (2022); she additionally provided the voice of Mary Jane Watson in Spider-Man: Into the Spider-Verse (2018). She appeared as Toast the Knowing in Mad Max: Fury Road (2015), and has starred in numerous independent films, including Dope (2015), Adam Green's Aladdin (2016), and Gemini (2017).
In addition to acting, Kravitz works as a fashion model and musician. As of 2017, she is the face of YSL Beauté. Kravitz has also starred in campaigns for Tiffany & Co., Vera Wang, Balenciaga, Alexander Wang, Coach New York, Tumi, and Calvin Klein. She fronts the band Lolawolf and released the albums Calm Down in 2014 and Tenderness in 2020.