Swank came to international recognition for her performances as Brandon Teena, a transgender man, in Kimberly Peirce's Boys Don't Cry (1999), and as Maggie Fitzgerald, an aspiring boxer, in Clint Eastwood's Million Dollar Baby (2004). Both of her performances earned her critical acclaim, and she earned numerous accolades, including two Academy Awards, two Golden Globe Awards, two Critics' Choice Movie Awards and a Screen Actors Guild Award. She was named by Time magazine as one of the 100 most influential people in the world in 2005.
Swank later ventured into producing with the films Amelia (2009), Conviction (2010), You're Not You (2014), and What They Had (2018), all of which she also starred in. Her other notable films include the television film Iron Jawed Angels (2004), and the feature films Freedom Writers (2007), Logan Lucky (2017), The Hunt (2020), and Fatale (2020).